منابع مشابه
Lorcaserin for weight management
Type 2 diabetes and obesity commonly occur together. Obesity contributes to insulin resistance, a main cause of type 2 diabetes. Modest weight loss reduces glucose, lipids, blood pressure, need for medications, and cardiovascular risk. A number of approaches can be used to achieve weight loss, including lifestyle modification, surgery, and medication. Lorcaserin, a novel antiobesity agent, affe...
متن کاملMulticenter, placebo-controlled trial of lorcaserin for weight management.
BACKGROUND Lorcaserin is a selective serotonin 2C receptor agonist that could be useful in reducing body weight. METHODS In this double-blind clinical trial, we randomly assigned 3182 obese or overweight adults (mean body-mass index [the weight in kilograms divided by the square of the height in meters] of 36.2) to receive lorcaserin at a dose of 10 mg, or placebo, twice daily for 52 weeks. A...
متن کاملCoadministration of lorcaserin and phentermine for weight management: A 12‐week, randomized, pilot safety study
OBJECTIVE To assess the short-term tolerability of lorcaserin alone or with two dose regimens of phentermine. METHODS This was a 12-week, randomized, double-blind, pilot safety study of N = 238 nondiabetic patients with obesity or overweight with ≥1 comorbidity randomized to lorcaserin 10 mg twice daily (BID; LOR BID) alone or with phentermine 15 mg once daily (QD; LOR BID+PHEN QD) or 15 mg t...
متن کاملFormulary management of 2 new agents: lorcaserin and phentermine/topiramate for weight loss.
BACKGROUND Obesity may lead to the development of multiple chronic disease states, including hypertension, dyslipidemia, and type 2 diabetes mellitus. Over a half billion adults worldwide are affected by obesity, and more than two-thirds of adults are either obese or overweight in the United States. Diet and exercise have been the mainstays of treatment in this population; however, once failed,...
متن کاملLorcaserin (Belviq)
INTRODUCTION In the U.S., obesity is prevalent in epidemic proportions, and rates continue to rise. Current data indicate that the combined prevalence of overweight and obese adults in the U.S. is 69.2%.1 The prevalence of obesity alone accounts for 35.7% of adults in the U.S., with men and women equally affected.2 In the U.S., approximately 18.4% of adolescents 12 to 19 years of age are obese....
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ژورنال
عنوان ژورنال: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
سال: 2013
ISSN: 1178-7007
DOI: 10.2147/dmso.s36276